Iam a Licensed /Certified/National Certified Male Therapist this is strictly a clinical massage it is for health and well being and for helping with pain management.I do massage for relaxation of muscles so there is more freedom of movement in the body so the body works more efficent and get more out of your day.If you just want to relax and get away from the stress and tension of the day then get a relaxing massage and rejunivate yourself to maximize the rest of the day and week. I also do Sport Massage for you that are getting ready for the ski season.Just think your racing down the mountain and out of nowhere you get a cramp because your muscles are not relaxed and open to the oxygen and vital body fluids.A Deep Tissue Massage before an event like this gives the body more stamina due to more efficeint oxygen to the muscles.
A therapeutic effect is a consequence of a medical treatment, of any kind, the results of which are judged to be desirable and beneficial. This is true whether the result was expected, unexpected, or even an unintended consequence of the treatment.
What constitutes a therapeutic effect vs. a side effect is a matter of both the nature of the situation in which a treatment is used and the goals of treatment.
In addition to (or in place of) the intended therapatizing effect of a treatment, a therapatizer may cause undesired (adverse) effects as well. When an adverse effect is weaker than the therapeutic effect, it is commonly referred to as a "side effect". An adverse effect may result from an unsuitable or incorrect dosage or procedure (which could be due to medical error). Some adverse effects occur only when starting, increasing or discontinuing a treatment. Using a drug or other medical intervention which is contraindicated may increase the risk of adverse effects. Patients sometimes quit a therapy because of its adverse effects. The severity of adverse effects ranges from nausea to death.Common adverse effects include alteration in body weight, change in enzyme levels, loss of function, or pathological change detected at the microscopic, macroscopic or physiological level.
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» Washington, Oct 24 ANI: In an epigenetic study, scientists have discovered genomic changes in the brains of people who committed suicide as a result of major depression. Epigenetics is the study of heritable changes in gene function that may occur without modifying the gene sequence, often as a consequence of environmental exposures. There are an increasing variety of epigenetic mechanisms that have been described, including the regulation of gene function via the methylation or demethylation of DNA. Led by Drs. Michael Poulter and Hymie Anisman, the research team compared the brain tissues of those who had major depressive disorder and committed suicide to those from a control group who died suddenly, from heart attacks and other causes. The researchers discovered that the genome was being chemically modified in individuals who have committed suicide as a result of major depression. A process that is normally involved in regulating cell development did the chemical modification. Poulter explained: "We have about 40,000 genes in every cell and the only reason a skin cell becomes a skin cell as opposed to a heart cell is because only a fraction of the genes are being expressed, and the other genes not being expressed are shut down by this genetic process of DNA methylation." The researchers discovered that the rate of methylation in the suicide brains was almost ten times that of the control group. They also found that the gene being shut down was a neurotransmitter receptor that plays a major role in regulating behavior. Dr. John H. Krystal, Editor of Biological Psychiatry and affiliated with both YaleUniversitySchool of Medicine and the VA ConnecticutHealthcare System, said: "This is exciting new evidence that genetic and environmental factors may interact to produce specific and long-lasting modifications in braincircuits. Further, these modifications may shape the course of one's life in extremely important ways, including increasing the risk for major depressive disorder and perhaps suicide." "The whole idea that the genome is so malleable in the brain is surprising, because brain cells don't divide. You get dealt your neurons at the start of life, so the idea that there are still epigenetic mechanisms going on is pretty unusual," added Poulter. The authors indicated that the above findings open an entirely new avenue of research and potential therapeutic interventions. The study was published in a recent issue of Biological Psychiatry. ANI" target="_blank">Genomic changes occur in brains of people who commit suicide - aniin.com
» Washington, Oct 24 ANI: In a study on rodents, scientists at the GladstoneInstitute of Neurological Disease GIND have identified a new method to destroy amyloid-beta AB proteins, characteristic of Alzheimer's disease AD. Led by Dr. Li Gan, the researcher team has discovered that it is possible to trigger the activity of a potent AB-degrading enzyme in mouse models of the disease by reducing its natural inhibitor cystatin C CysC. Earlier, the researchers had shown that cathepsin B CatB is an AB-degrading enzyme present in allhumans, and now researchers have put forth a highly effective approach to promote CatB-mediated clearance of AB. "Many groups have developed drugs to block the production of AB, but the efficacy and safety of this approach remains to be demonstrated in clinical trials. By identifying an effective strategy to enhance the removal of AB, this research provides a very promising alternative or complementary therapeutic avenue," said GIND Director Dr. Lennart Mucke. "Our strategy to harness the activity of a powerful AB-degrading enzyme takes advantage of the brain's own defense system to remove the toxic AB build-up. In principle, one could boost the activity of CatB by expressing more of it in the brain or by reducing the activity of CysC, its natural inhibitor. We focused on the latter strategy because it has greater long-term therapeutic potential," said Gan. Most of the enzymes that degrade proteins are kept in check by regulators called protease inhibitors. Similarly, the protease inhibitor CysC regulates the activity of CatB. By reducing CysC activity, the scientists were able to unleash the AB-degrading power of CatB, effectively preventing the build-up of AB in mouse models of AD. The researchers measured brain cell activities that relate closely to learning and memory for analysing the impact of the manipulation on brain function. Increasing CatB activity by lowering CysC levels prevented AB-induced deficits in those cellularactivities. They also tested the modified AD mice for learning and memory in a water maze. Higher levels of CatB activity improved the ability of AD to learn the maze and to retain the new information. Increasing CatB activity also prevented the premature mortality that is typically seen in these Alzheimer models. "Our results suggest that CysC reduction has major therapeutic potential. The next step will be to develop pharmacological approaches to inhibit CysC in the humanbrain," said Gan. The study was published in the latest issue of the journal Neuron. ANI" target="_blank">New strategy to eliminate toxic proteins from brains of Alzheimer's patients - aniin.com
» International/Science Snail toxin could provide relief from painSydney, Oct 24 IANS The toxins with which cone snails immobilise their prey, could potentially offer better painrelief in the future, according to research. Neuroscientists at University of Queensland's BrainInstitute QBI have revealed that a toxin produced by a lethal cone snail acts on a newly identified target and cell signalling pathway that may play a critical role in regulating chronic pain. The venom of cone snails - marineanimals found in several of the world's oceans - is currently the subject of extensive scientific investigation because its powerful analgesic pain relieving properties are thought to offer several distinct advantages over traditional therapeutic treatments for neuropathic pain. Professor DavidAdams and his team have identified specific peptides in the cone shell toxin that may serve as the molecular framework for novel "designer" conotoxins, according to a Queensland press release. "For several years, it's been known that the remarkable properties of cone shell toxins conotoxins hold tremendous promise for chronic pain sufferers, and drugs that can combat or alleviate pain are a holy grail in drug discovery," Adams said. The prevailing scientific view until now has been that conotoxins only targeted one group of pain receptors. However, Adams, along with David Craik UQ's Institute for Molecular Bioscience and colleagues have described a surprising new way of inhibiting pain sensors using mini-proteins commonly found in cone snail venoms. These findings were published in the Journal of Neuroscience. --Indo-Asian NewsService st/pb/dg 262 Words 24101313 " target="_blank">Snail toxin could provide relief from pain - IANS.in
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